All odds via FanDuel Sportsbook.
- Tennessee Titans @ Cleveland Browns: -3.5
- Los Angeles Chargers @ Minnesota Vikings: -1.5
- New England Patriots @ New York Jets: +2.5
- Houston Texans @ Jacksonville Jaguars: -7.5
- Buffalo Bills @ Washington Commanders: +6.5
- Indianapolis Colts @ Baltimore Ravens: -8
- Atlanta Falcons @ Detroit Lions: -3
- New Orleans Saints @ Green Bay Packers: -1.5
- Denver Broncos @ Miami Dolphins: -6.5
- Carolina Panthers @ Seattle Seahawks: -5
- Chicago Bears @ Kansas City Chiefs: -13.